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S
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Presents
the Friday Keck Center Teleconference*
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Modeling
and Reconstructing Non-treelike Evolutionary Relationships in
Species and Populations
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Luay
Nakhleh, Ph.D.,
Assistant
Professor, Computer Science
Rice
University
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4:00
pm Friday
6th
Oct. , 2006
(Refreshments
at 3:45)
5.521
Levin Hall
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Abstract: Ever since
the theory of evolution was introduced, inferred evolutionary
relationships have for the most part taken the shape of a tree. At
the species level, evolutionary trees (also known as
phylogenies)have been reconstructed to model speciation and
divergence of organisms. At the population level, particularly the
human population, large resources have been dedicated to inferring
haplotypes and reconstructing their trees. Whereas trees provide
a good first approximation for modeling evolutionary relationships
of several groups of organisms, as well as various haplotype
regions, they may be inadequate for other groups of organisms, and
for haplotype data in general. Species-level evolutionary events,
such as hybrid speciation (e.g., in groups of plants, fish, and
frogs) and horizontal gene transfer (e.g., in bacteria and groups
of plants), cannot be modeled by trees. Instead, the appropriate
model of evolutionary relationships when these events occur is
Phylogenetic Networks. Further, meiotic recombination among
haplotypes may result in evolutionary relationships best modeled
by Ancestral Recombination Graphs. In this talk, I will describe
our recent work on (1) models of these events, (2) optimization
criteria for their accurate reconstruction, and (3) efficient
algorithms for computing solutions based on these criteria..
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The
Keck Friday Seminar*
schedule
for Fall 2006
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25-Aug
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Monte Pettitt, Chair,
KEC, Professor, Dept. of Chemistry, UH
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Overview of
Keck Center and GCC (5.520 Levin
Hall)
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1-Sept
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Labor
Day Weekend
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8-Sept
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Dr. Steen Pedersen,
Assoc. Professor, BCM, Dept. of Physiology and Biophysics
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Conformational
Regulation and Electrostatics of the Nicotine Acetylcholine
Receptor
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15-Sept
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Dr. C. J. Peters, M.D.,
Professor, Director for Biodefense, Center
for Biodefense and Emerging Infectious Diseases, UTMB
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Rift
Valley Fever: Adventures in Control and Vaccine Development.
***LIVE
FROM UTMB
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22-Sept
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Jacqueline
Northcut Waugh
President
and CEO,
BioHouston
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Reaching
for critical mass in Biotech (5.520
Levin Hall)
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29-Sept
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Dr. James Inglese, Dir,
Biomolocular Screening & Profiling, NIH, Nat’l Human Genome
Research Institute, Chemical Genomics Center
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Quantitative
High Throughput Screening: Discovery of Investigational Molecular
Probes through the Biological Activity Profiling of Chemical
Libraries
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6-Oct
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Luay
Nakhleh
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Non-treelike
Evolutionary Relationships
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13-Oct
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Keck
Annual Research Conference
https://cohesion.rice.edu/services/eventreg/?event=ARC6
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Edwin
Hornberger Conference Center, Texas Medical Center
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20-Oct
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Marek Kimmel,
Professor, Statistics, Rice
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TBA
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27-Oct
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TBA
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(5.520
Levin Hall)
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3-Nov
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CMB/SCBMB
Retreat
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10-Nov
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TBA
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TBA
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17-Nov
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Rigoberto Advincula,
Assoc. Prof, Chemistry, UH
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TBA
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24-Nov
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Thanksgiving
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1-Dec
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Ruth Nussinov, Sr.
Prin. Scien, Nat’l Cancer Institute, Center for Cancer Res,
Computational Structural Biology Group
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TBA
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KECK/HAMP
Friday Seminars: http://xray.utmb.edu/keck
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Archived
Friday Seminar Webcasts Available:
http://cohesion.rice.edu/centersandinst/gcc/
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*Improved
clearer images: Now with POLYCOM's
DUAL STREAMING H.239 technology for clear
high-resolution slides plus video.
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