Presents the Friday Keck Center Teleconference*


The Drug Development Crisis: Efficiency and Safety


C. Thomas Caskey, M.D., F.A.C.P. ,

Director and COO, Institute for Molecular Medicine

UT Health Science Center Houston


4:00 pm Friday

Feb. 23rd , 2007

(Refreshments at 3:45)

5.521 Levin Hall

Abstract: Despite advancements in genetics, chemistry, and protein engineering, recent years have seen fewer approvals of new drugs, increases in development costs, and high-profile drug withdrawals. This article focuses on technologic methods for improving drug development efficiency. These technologies include high-content cell screening, expression profiling, mass spectroscopy, mouse models of disease, and a post-launch screening program that enables investigations of adverse drug effects. Implementation of these new technologies promises to improve performance in drug development and safety.

(http://www.uth.tmc.edu/uth_orgs/imm/faculty/caskey.htm)



The Keck Friday Seminar*

schedule for Spring 2007

12-Jan

Robert Cox

Functional MRI

19-Jan

Ching Lau, Assoc Prof, Pediatrics, Hematology/Oncology, BCM

Novel targets in pediatric brain tumors: from genomics to bedside

26-Jan

Irina I. Serysheva

Baylor College of Medicine

Domain Structure of RyR1 channel at Subnanometer Resolution

2-Feb

Poster winners from the 2006 Keck Annual Research Conference

TBA

9-Feb

Mauro Ferrari, Professor, Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases; Chairman, Dept. of Biomedical Engineering, UTHSC-H

Biomedical Nonotechnology

16-Feb

Mike Mancini, Associate Professor, Dept. of Molecular & Cellular Biology, BCM

Single cell analyses of transcription using high throughput imaging

23-Feb

C. Thomas Caskey, Dir. and COO, Institute for Molecular Medicine, UTHSC-H

The Drug Development Crisis: Efficiency and Safety

2-Mar

Jack Smith, Dean & Professor, School of Health Information Sciences, UTHSC-H

Issues Related to Open Access and Clinical Data Repositories

9-Mar

Midterm Recess


16-Mar

Vittorio Cristini, Associate Professor, School of Health Information Sciences, UTHSC-H

TBA

23-Mar

Margaret Cheung, Assistant Prof, Physics, UH

TBA

30-Mar

Theodore S. Jardetzky

Northwestern University

Professor, Biochemistry, Molecular Biology & Cell Biology

TBA

6-Apr

Good Friday


13-Apr

Keith Hodgson, Prof. Chemistry, Stanford Synchrotron Radiation Laboratory, Stanford University

TBA

20-Apr

Stanley Lemon, Dir, Institute for Human Infections and Immun; Professor, Internal Medicine-Infectious Diseases, Microbiology, UTMB

Interactions of the hepatitis C virus RNA-dependent RNA polymerase NS5B with the retinoblastoma tumor suppressor protein

KECK/HAMP Friday Seminars: http://xray.utmb.edu/keck

Archived Friday Seminar Webcasts Available: http://cohesion.rice.edu/centersandinst/gcc/

*Improved clearer images: Now with POLYCOM's DUAL STREAMING H.239 technology for clear high-resolution slides plus video.