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Presents
the Friday Keck Center Teleconference*
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Brighter
than a Quadrillion Suns:
X-ray
Free Electron Lasers and Applications in Structural Dynamics and
Biology
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Keith
Hodgson, Ph.D.,
Prof.,
Dept. Chemistry, SSRL, Stanford University
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4:00
pm Friday
April
13th , 2007
(Refreshments
at 3:45)
5.521
Levin Hall
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Abstract: Much of our
understanding of structure and function of objects in the chemical
and biological nanoworld - from drugs interacting with their
biological targets to the action of large "molecular
machines" responsible for key processes like DNA
transcription and protein synthesis - comes from "seeing the
invisible". X-rays enable us to see the arrangement of
individual atoms and study structures. Today's state of the art
x-ray sources, called synchrotrons, provide exquisite detail for
such studies but lack the brightness to investigate materials as
they undergo movements on the atomic scale. This will all change
in 2009 with the first operation at Stanford of a x-ray free
electron lasers (called LCLS) whose brightness will surpass
today's brightest x-ray sources by about 10 billion times! This
lecture will illustrate how such x-ray laser radiation will be
produced and the science it will enable - from studying structural
dynamics in "real time" to the imaging of large,
non-crystalline nanostructured materials.
(
http://www.stanford.edu/dept/chemistry/faculty/hodgson/
)
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The
Keck Friday Seminar*
schedule
for Spring 2007
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12-Jan
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Robert
Cox
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Functional
MRI
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19-Jan
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Ching Lau, Assoc Prof,
Pediatrics, Hematology/Oncology, BCM
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Novel
targets in pediatric brain tumors: from genomics to bedside
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26-Jan
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Irina
I. Serysheva
Baylor
College of Medicine
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Domain
Structure of RyR1 channel at Subnanometer Resolution
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2-Feb
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Poster winners from the
2006 Keck Annual Research Conference
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Matthew
Baker, Kexin Huang, & Jeffrey Reid
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9-Feb
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Mauro Ferrari,
Professor, Brown Foundation Institute of Molecular Medicine for
the Prevention of Human Diseases; Chairman, Dept. of Biomedical
Engineering, UTHSC-H
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Biomedical
Nonotechnology
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16-Feb
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Mike Mancini,
Associate Professor, Dept. of Molecular & Cellular Biology,
BCM
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Single cell
analyses of transcription using high throughput imaging
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23-Feb
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C. Thomas Caskey, Dir.
and COO, Institute for Molecular Medicine, UTHSC-H
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The Drug
Development Crisis: Efficiency and Safety
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2-Mar
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Jack Smith, Dean
& Professor, School of Health Information Sciences, UTHSC-H
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Issues
Related to Open Access and Clinical Data Repositories
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9-Mar
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Midterm
Recess
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16-Mar
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Vittorio Cristini,
Associate Professor, School of Health Information Sciences,
UTHSC-H
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Computational
modeling identifies morphologic predictors of tumor invasion
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23-Mar
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Margaret
Cheung, Assistant Prof, Physics, UH
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Life in a
crowd: macromolecular crowding and confinement effects on protein
interactions in living systems
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30-Mar
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Theodore
S. Jardetzky
Northwestern
University
Professor,
Biochemistry, Molecular Biology & Cell Biology
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Structural
Insights into the Metastable Folding, Refolding and Membrane
Fusion Activity of the Paramyxovirus F Protein.
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6-Apr
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Good
Friday
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13-Apr
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Keith Hodgson, Prof.
Chemistry, Stanford Synchrotron Radiation Laboratory, Stanford
University
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Brighter
than a Quadrillion Suns:
X-ray Free
Electron Lasers and Applications in Structural Dynamics and
Biology
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20-Apr
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Stanley Lemon,
Dir, Institute for Human Infections and Immun; Professor, Internal
Medicine-Infectious Diseases, Microbiology, UTMB
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Interactions
of the hepatitis C virus RNA-dependent RNA polymerase NS5B with
the retinoblastoma tumor suppressor protein
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KECK/HAMP
Friday Seminars: http://xray.utmb.edu/keck
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Archived
Friday Seminar Webcasts Available:
http://cohesion.rice.edu/centersandinst/gcc/
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*Improved
clearer images: Now with POLYCOM's
DUAL STREAMING H.239 technology for clear
high-resolution slides plus video.
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